FAQ - Frequently Asked Questions about Celox (2023)

1. What is Celox?

Celox is a very effective haemostat granule. It is made of aproprietary composition which contains chitosan. Chitosan is a natural polymer extracted from shrimp shells and highly purified. Celox’s composition is protected by 3 international patent applications.

2. How does Celox work?

Celox™ granules are very high surface area flakes. When they come in contact with blood, Celox™ swells, gels, and sticks together to make a gel like clot, without generating any heat. It works independently of the body’s normal clotting mechanism and can clot hypothermic or even heparinised blood.

3. Where can I get the product?

Celox is sold through a network of distributors. To find out who represents Celox in your area, please contactceloxenquiries@medtrade.co.uk detailing what country you are in with details about your intended use.

(Video) Hemostatic Vs. Non-Hemostatic Gauze (what you need to know)

4. Is Celox a Pharmaceutical?

No. Celox products are Class III CE Marked Medical Devices and approved by BSI.

5. Will Celox stop life-threatening bleeding?

Yes, if applied to the bleeding vessel Celox can stop life-threatening bleeding from a severed artery. This has been demonstrated independently in laboratory testing and evidenced in actual battlefield use.

6. Will Celox clot blood containing anticoagulants such as Heparin?

Yes, Celox has been tested and proven to clot blood containing Heparin and Coumadin (generic name warfarin).

7. Will Celox clot hypothermic blood?

Yes, Celox has been tested and proven to clot blood as cool as 15°C. BSI have reviewed these tests as part of our class III CE Mark.

8. Can Celox be easily removed from a wound?

Yes. In cases of emergency bleeding, Celox should be left in the wound until the patient in seen by medical facility personnel. It can then be easily removed. Remove as much as possible by hand, then irrigate the wound with water or saline. In cases of minor bleeding Celox can be removed once the wound has stabilized. This can be as short as 10 minutes. Irrigate with water or saline. Chitosan is a natural polysaccharide (polymer made of sugars) and has been shown to be broken down to basic sugars (glucosamine & n-acetyl glucosamine) by lysozyme, one of the body’s normal enzymes. Celox™ does NOT use non degrading procoagulant minerals or nano particles such as kaolin, smectite or zeolite, which will remain in the body indefinitely unless completely removed.

(Video) Bleeding Control with Celox and Toni Murch

9. What Shelf life does Celox have?

Celox Granules and Celox-A Applicator have a shelf life of 4 years from the point at manufacture. Celox Gauze and Celox Rapid Gauze have a 5 year shelf life. Each product pack is marked with an expiration date.

ProductShelf Life
Celox Granules 15g4 Years from manufacture
Celox-A, Applicator4 Years from manufacture

Celox Gauze
10ft roll & 5ft Z-fold

5 Years from manufacture

Celox Rapid
5ft Z-fold

5 Years from manufacture

10. How much is needed to treat a life-threatening wound?

All wounds are different but the 5-foot gauze has been tested and stopped bleeding from a major artery, as has the 15 g granules. The larger sizes (10 foot gauze) give additional security for more complex injuries or multiple wounds on one casualty.

11. Will Celox adversely affect later wound healing?
No. Celox has been tested to show that wound healing continues normally after its use.

12. Does Celox generate heat?

No. Celox has been tested and shown not to generate any increase in heat during blood clotting.

13. How is Celox used?

Celox use is easy. Pour, Pack And Press.

  • Pour on to the area of the wound.
  • Pack any cavity with either Celox or gauze.
  • Press. Compress the wound to push the Celox into place and stop blood flow for a short period while the Celox clot develops and strengthens.

The amount of time and pressure required depends on the pressure at which blood is coming out of the body. For life-threatening bleeding strong pressure for 1 minute (with Celox Rapid), 3 minutes (with Celox Gauze) or 5 minutes (with granules). Should a wound start to re-bleed (and you believe Celox was put over the bleeding area) then just hold pressure for longer. If you suspect Celox is no longer contacting the area where the bleeding is coming from, then remove and apply a fresh pack. Additional packs can be used if required.

(Video) Know Your S#!T | Wound Packing - Quikclot 🩸

14. Are there any contraindications?

Celox is not intended for internal (surgical) use. Celox should not be used in the eyes. It is not indicated for use in the mouth.

15. What if I get it in my eyes?

If eye irritation occurs, flush with water for five minutes.

16. Which is the best product for me to use?

The best version depends on your application. The best place to start is to read the product section at the foot of the relevant users’ page, whether military, security and close protection services, police, first responder, paramedic, or humanitarian relief. These describe the most relevant products for each user.

17. Do people with shellfish allergies have allergic reaction to Celox as a result of the chitosan?

There have been no known or suspected allergic reactions as a result of using Celox since its launch in 2006. The chitosan has been extensively tested on individuals with suspected and confirmed shellfish allergy, none of the test subjects demonstrated any dermal sensitivity when tested against the chitosan material.

18. Where can I find the latest safety data sheets?
Safety Data Sheets (SDS) can be downloaded from celoxmedical.com following this link – Click here

19. What happens if I accidentally consume Celox?
Do not eat. Celox is non-toxic but not recommended for consumption. Celox absorbs moisture when in contact with fluid and can absorb moisture from the gut which may cause discomfort. If ingested, drink copious amounts of water to avoid any discomfort.
For the latest Safety Data Sheets please follow this link – Click here

(Video) Introduction to the Hemostatic Challange! Celox v Quickclot

20. Is Celox a powder?
No, Celox granules are macroscopic granular flakes prepared from Chitosan, a material derived from Chitin which is found naturally in crustacean exoskeleton or shell. Celox is different from some other hemostatic agents that contain minerals such as Zeolite or Kaolin that are released as nanoscale powders when in contact with fluid.

21. How do I store Celox?
Celox products should be stored in dry conditions at ambient temperature and no special storage conditions are required or indicated on the product labelling. Stability studies of Celox products stored at temperatures of 60°C and 40°C and freeze-thaw studies have been completed with no detrimental results to product or packaging reported.
Discard any remaining product after use assterility will be compromised.
Re-use potentially poses a risk of infection.

22. How many times can you use Celox to treat wounds and how many wounds?
Celox products are provided sterile for single use. Celox can be used to treat several wounds on one casualty.
Do not store unused opened packs of Celox for later use. Products sterility and performance may be affected.

23. Can I use Celox on the Head or Neck?
Celox can be used on the head (for injuries outside of the skull) and neck. Refer to your clinical guidelines and or training, for example: Treatment of injuries in these areas needs to consider the airway and major blood vessels that supply the brain and the risk of applying pressure to the brain and nervous tissue in the event of a fracture. Celox is not approved for use inside of the mouth.

24. Can I use Celox on the Chest or abdomen?
Wounds to the chest or abdomen are generally classed as non-compressible. Most guidelines e.g. TCCC say do not use haemostatics on non-compressible wounds. Refer to your clinical guidelines and or training. In an extreme situation this requires clinical judgement. Use of Celox on this part of the body is not contraindicated. For penetrating chest injuries the recommended treatment to prevent tension pneumothorax is to use an occlusive seal such as Foxseal.

25. Does Celox work on patients with Haemophilia / Von Willebrand Disease?
Von Willebrand disease is a genetic disorder caused by missing or defective Von Willebrand Factor (VWF) a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process.
Celox works by purely physically means and does not rely on the body’s own blood clotting mechanisms36. While we do not have testing on patients with Haemophilia, Celox has been tested on blood containing Warfarin and Heparin as well as being tested on hypothermic blood. In all ofthese cases Celox continued to work as well as on normal blood.

(Video) Preguntas Frecuentes: Celox agente hemostático

26. How long can Celox be left in place in a wound?
Case reports have shown Celox has been left in place for 24 hours where there was no re-bleed or leakage. We recommend leaving Celox in place until the patient is moved to definitive care.


How long can you leave Celox on a wound? ›

Celox can safely be left on a wound for up to 24 hours however do not delay moving patient to definitive care.

Can you put Celox in the neck? ›

Celox can be used on the head (for injuries outside of the skull) and neck.

How do you remove Celox from a wound? ›

Celox can be removed by irrigating the wound with water or saline once clotting has occurred. This product is available in both the granular and bandage forms.

Where can Celox be used? ›

CELOX trauma treatments include advanced bandages that rapidly stop lethal bleeding and dressings designed to quickly seal wounds that penetrate the chest wall. CELOX RAPID Gauze is a hemostatic agent – it is designed to stop external bleeding from gunshot injuries, stab, blast wounds and other bleeding injuries.

When should you not apply a hemostatic dressing? ›

Contraindications: 1. Wounds of the abdomen, chest, or open skull fractures.

How long does it take for hemostatic gauze to work? ›

These products, on average, and again, with the proper technique, may stop blood flow in as little as 3 minutes. Some products, such as Celox Rapid, are purported to stop bleeding in as little as 90 seconds. With standard gauze, it could take 10 minutes or more to fully stop blood flow!

Does hemostatic gauze dissolve? ›

is a sterile product ready for immediate use out of the package, and can quickly and easily be cut or packed to appropriate size to fit in tight oral spaces. Surgi-StopTM dressing dissolves in a few days and is safe if swallowed.

Does the military use Celox? ›

hemostatic agents for military-wide use. Already in use by US Special Forces due to it's superior results, the approval of the CoTCCC makes Celox Gauze a standard ordering and procurement hemostatic dressing for all branches of the US military.

What is the difference between QuikClot and Celox? ›

Both of these dressings are made of common gauze with an impregnated component. Celox is gauze with chitosan granules, QuikClot CG is gauze with kaolin mineral powder. Chitosan is a weak hemostatic agent, a product of shellfish endoskeleton that has been known to cause an allergic response in some patients.

Can zeolite cause blood clots? ›

In summary, zeolite released Ca2+ and absorbed Na+ and K+ upon contact with the blood via a cation exchange reaction. The increase in Ca2+shortened both the APTT and clot formation time in vitro. Cation exchange is an important mechanism of action underlying the hemostatic effect of zeolite.

What stops bleeding fast? ›

Stop the bleeding
  • Have the injured person lie down and elevate the site that is bleeding.
  • Remove any visible objects in the wound that are easy to remove. ...
  • Remove or cut clothing from around the wound. ...
  • Apply steady, direct pressure and elevate the area for a full 15 minutes.

How do you clean a wound that won't stop bleeding? ›

rinse the wound under running tap water for 5 to 10 minutes. soak a gauze pad or cloth in saline solution or tap water, or use an alcohol-free wipe, and gently dab or wipe the skin with it – don't use antiseptic as this may damage the skin.

What is the proper way to use hemostatic agents? ›

If using roll gauze impregnated with the hemostatic agent, tightly pack the unraveled gauze directly into the bleeding site. Pack as much of the dressing into the wound as possible. 6. Pack the remaining wound cavity with standard gauze.

What is the active ingredient in Celox rapid? ›

Celox Rapid contains Chito-R™ activated chitosan granules that stick to wet tissue in the wound*. Chito-R™ forms an adhesive gel that seals the wound to stop the flow of blood, speeding up compression time.

How long can hemostatic dressing stay on? ›

The dressing may be left in place for up to 24 hours. Gently remove dressing. If the dressing is difficult to remove, hydrate with sterile saline. At the end of the procedure, thoroughly irrigate the wound to remove kaolin that may be released from the dressing.

How often should a bleeding wound dressing be changed? ›

Change the bandage each day—or sooner, if it becomes dirty or wet—to keep the wound clean and dry. Some wounds, such as scrapes that cover a large area, should be kept moist to help reduce scarring.

How do you dress a wound when there is active bleeding? ›

Open the clothing over the bleeding wound. Wipe away any pooled blood. Pack (stuff) the wound with bleeding control gauze (preferred), plain gauze, or clean cloth. Apply steady pressure with both hands directly on top of the bleeding wound.

Do hemostatic clips fall off? ›

The clip will fall out on its own. This usually happens within a few weeks. Some clips are in patients longer. The clip is very small, so you will not notice when the clip passes out in your stool.

How many times a day should you change gauze? ›

How often should you change wound dressing?
Dressing TypeWhen to Change (unless stated otherwise)
Dressing for moderate exudate woundEvery 2-3 days. When the dressing is soiled but not soaked
Dressing for high exudate woundAt least daily. Whenever the dressing is saturated
8 more rows
Sep 6, 2022

How long should direct pressure be applied onto a packed hemostatic dressing? ›

Quickly apply pressure until bleeding stops. Hold continuous pressure for 3 minutes. Reassess to ensure bleeding is controlled.

How long should you put antibiotic ointment on a cut? ›

Bacitracin or Polysporin ointment is OK to use for 1-2 weeks 5. Cover the wound with a band-aid or nonstick gauze pad and paper tape. 6. Repeat wound care once a day until wound is completely healed with no open or draining areas.

Can you leave blood stop in a wound? ›

A: It can be left on as long as necessary to stop bleeding. When the bleeding has stopped, BloodSTOP® can be removed from surface wounds by rinsing with sterile water or saline solution and gentle wiping so as not to disturb the wound. Q: Can I use BloodSTOP® on my pets?

How long should you keep an infected wound covered? ›

A handful of studies have found that when wounds are kept moist and covered, blood vessels regenerate faster and the number of cells that cause inflammation drop more rapidly than they do in wounds allowed to air out. It is best to keep a wound moist and covered for at least five days.

Can I leave a bloody bandage on? ›

This is called bleed-through and ideally, bandages should be changed before this occurs. Bleed-through increases the danger that a bandage will adhere to the wound. When this happens, soak the dressings and coax it off gently.

Do wounds heal better covered or uncovered? ›

Wounds need to be covered so that they can heal properly. When a wound is left uncovered, the new surface cells that are being created can easily dry out. When these important cells dry out, it tends to slow down the healing process. A wound should be covered using a clean bandage.

What helps wounds heal faster? ›

Wounds heal faster if they are kept warm. Try to be quick when changing dressings. Exposing a wound to the open air can drop its temperature and may slow healing for a few hours. Don't use antiseptic creams, washes or sprays on a chronic wound.

What speeds up wound healing? ›

Healthy foods rich in nutrients like vitamin A, C, potassium and zinc provide your body with the fuel it needs to speed up wound healing. Power foods like dark, leafy greens, as well as ginger, mushrooms, beets and yoghurt will also help your body heal wounds faster.

What naturally stops bleeding fast? ›

Top 10 ways to stop the bleeding with immediate effects
  • Try to elevate the wound above the heart. ...
  • Ice treatment. ...
  • Apply tea bags. ...
  • Witch Hazel. ...
  • Zinc lozenge and Victim C powder. ...
  • Petroleum Jelly. ...
  • Mouthwash. ...
  • Use styptic pencil.

What are the 4 ways to stop bleeding? ›

Fertel shares the steps to take with a small cut.
  • Apply pressure. Place clean gauze or cloth on the wound and apply direct pressure. ...
  • Elevate. If the cut is on your legs or arms, elevate the limb above heart level to slow the blood flow. ...
  • Wash the wound. ...
  • Bandage it up. ...
  • First-aid kit items for deep cuts.
Oct 27, 2021

What is the white powder used to stop bleeding? ›

Description. BleedStop is an FDA organic non-stinging powder that stops bleeding in seconds. BleedStop can be used on all minor cuts and major wounds. 100% safe for ALL wounds.

Is it bad if gauze sticks to wound? ›

If the dressing is stuck, soak with water or saline and wait for the dressing to loosen – allow a bit of time and avoid pulling as this will be painful and will damage the wound.

What home remedy helps wounds heal faster? ›

  1. Aloe (Aloe vera), as a cream or gel. ...
  2. Calendula (Calendula officinalis), or pot marigold, as an ointment or a tea applied topically. ...
  3. Marshmallow (Althaea officinalis) as a topical ointment to help wounds heal and fight inflammation.
  4. Tea tree oil (Melaleuca alternifolia) as oil or cream.

What is the best cream to heal wounds? ›

3 Great Over-the-Counter Ointments for Wound Care
  • Bacitracin. Bacitracin can be found in just about every over-the-counter antibiotic ointment on the market. ...
  • Bacitracin and Polymyxin B (Polysporin) The common brand name for this medication is Polysporin. ...
  • Bacitracin, Polymyxin B, and Neomycin (Neosporin)
Sep 27, 2022

What to do if blood comes through bandage? ›

If blood comes through the dressing, remove it and reapply pressure with a new dressing or pad to control the bleeding. Once the bleed is under control, secure in place with the bandage, tying the knot over the wound to keep the pressure on.

How often should you change gauze on a wound? ›

HOW OFTEN SHOULD DRESSINGS BE CHANGED? Once the initial bandage is removed, dressings should be changed as often as needed to keep wound drainage from soaking the gauze. This is usually one to four times a day. If you find that the bandage is wet with drainage when you change it, then change it more often.


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